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Frailty and Deconditioning
Frailty and Deconditioning
Selected articles and automatically-renewing searches covering the topics of frailty and deconditioning
Core Concepts
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PubMed Alerts
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Core Concepts
Cederholm TE, Bauer JM, Boirie Y, Schneider SM, Sieber CC, Rolland Y. Toward a definition of sarcopenia. Clin Geriatr Med. 2011 Aug;27(3):341-53. doi: 10.1016/j.cger.2011.04.001. PubMed PMID: 21824551.Cigolle CT, Ofstedal MB, Tian Z, Blaum CS. Comparing models of frailty: the Health and Retirement Study. J Am Geriatr Soc. 2009 May;57(5):830-9. Epub 2009 Apr 21. PubMed PMID: 19453306
Clegg A, Young J. The frailty syndrome. Clin Med. 2011 Feb;11(1):72-5.Review. PubMed PMID: 21404792
Fried LP, Ferrucci L, Darer J, Williamson JD, Anderson G. Untangling the concepts of disability, frailty, and comorbidity: implications for improved targeting and care. J Gerontol A Biol Sci Med Sci. 2004 Mar;59(3):255-63. PubMed PMID: 15031310.
Fried LP, Tangen CM, Walston J, Newman AB, Hirsch C, Gottdiener J, Seeman T, Tracy R, Kop WJ, Burke G, McBurnie MA; Cardiovascular Health Study Collaborative Research Group. Frailty in older adults: evidence for a phenotype. J Gerontol A Biol Sci Med Sci. 2001 Mar;56(3):M146-56. PubMed PMID: 11253156.
Rockwood K, Mitnitski A. Frailty defined by deficit accumulation and geriatric medicine defined by frailty. Clin Geriatr Med. 2011 Feb;27(1):17-26.PubMed PMID: 21093719.
Walston J, Hadley EC, Ferrucci L, Guralnik JM, Newman AB, Studenski SA, Ershler WB, Harris T, Fried LP. Research agenda for frailty in older adults: toward a better understanding of physiology and etiology: summary from the American Geriatrics Society/National Institute on Aging Research Conference on Frailty in Older Adults. J Am Geriatr Soc. 2006 Jun;54(6):991-1001. PubMed PMID: 16776798.
Xue QL. The frailty syndrome: definition and natural history. Clin Geriatr Med. 2011 Feb;27(1):1-15. Review. PubMed PMID: 21093718
Key Review Articles
Drey M, Pfeifer K, Sieber CC, Bauer JM. The Fried frailty criteria as inclusion criteria for a randomized controlled trial: personal experience and literature review. Gerontology. 2011;57(1):11-8. PubMed PMID: 20407227.
Fletcher K. Optimizing reserve in hospitalized elderly. Crit Care Nurs Clin North Am. 2007;19( 3):285-302, vi.
Gill TM, Allore HG, Holford TR, Guo Z. Hospitalization, restricted activity, and the development of disability among older persons. JAMA. 2004;292( 17):2115-2124.
Graf C. Functional decline in hospitalized older adults. Am J Nurs. 2006;106( 1):58-67, quiz 67-8.
Hubbard RE, Woodhouse KW. Frailty, inflammation and the elderly.Biogerontology. 2010 Oct;11(5):635-41.. PubMed PMID: 20571864.
King BD. Functional decline in hospitalized elders. Medsurg Nurs. 2006;15( 5):265-71; quiz 272
Sternberg SA, Wershof Schwartz A, Karunananthan S, Bergman H, Mark Clarfield A. The identification of frailty: a systematic literature review. J Am Geriatr Soc. 2011 Nov;59(11):2129-38. doi: 10.1111/j.1532-5415.2011.03597.x. . PubMed PMID: 22091630.
Epidemiology
Cigolle CT, Langa KM, Kabeto MU, Tian Z, Blaum CS. Geriatric conditions and disability: The health and retirement study. Ann Intern Med. 2007;147( 3):156-164Hubbard RE, Rockwood K. Frailty in older women. Maturitas. 2011 Jul;69(3):203-7. PubMed PMID: 21570783.
Hung WW, Ross JS, Boockvar KS, Siu AL. Recent trends in chronic disease,impairment and disability among older adults in the United States. BMC Geriatr. 2011 Aug 18;11:47. PubMed PMID: 21851629
Rockwood K, Song X, Mitnitski A. Changes in relative fitness and frailty across the adult lifespan: evidence from the Canadian National Population Health Survey. CMAJ. 2011 May 17;183(8):E487-94. PubMed PMID: 21540166
Pathophysiology
Fedarko NS. The biology of aging and frailty. Clin Geriatr Med. 2011 Feb;27(1):27-37. PubMed PMID: 21093720
Ho YY, Matteini AM, Beamer B, Fried L, Xue QL, Arking DE, Chakravarti A,Fallin MD, Walston J. Exploring biologically relevant pathways in frailty. J Gerontol A Biol Sci Med Sci. 2011 Sep; 66(9):975-9. PubMed PMID: 21743092
Marzetti E, Leeuwenburgh C. Skeletal muscle apoptosis, sarcopenia and frailty at old age. Exp Gerontol. 2006;41( 12):1234-1238.
Xue QL. The frailty syndrome: definition and natural history. Clin Geriatr Med. 2011 Feb;27(1):1-15. Review. PubMed PMID: 21093718
Weiss CO. Frailty and chronic diseases in older adults. Clin Geriatr Med. 2011 Feb;27(1):39-52.. PubMed PMID: 21093721.
PubMed Alerts
Continuously updated articles addressing frailty in older adults
Frailty/Deconditioning
Assessment and Management
Buurman BM, van Munster BC, Korevaar JC, de Haan RJ, de Rooij SE. Variability in measuring (instrumental) activities of daily living functioning and functional decline in hospitalized older medical patients: a systematic review. J Clin Epidemiol. 2011 Jun;64(6):619-27.. PubMed PMID: 21074969.Conroy SP, Stevens T, Parker SG, Gladman JR. A systematic review of comprehensive geriatric assessment to improve outcomes for frail older people being rapidly discharged from acute hospital: 'interface geriatrics'. Age Ageing. 2011 Jul;40(4):436-43.. PubMed PMID: 21616954.
de Morton NA, Keating JL, Jeffs K Exercise for acutely hospitalised older medical patients.Cochrane Database Syst Rev. 2007;(1)( 1):CD005955.
Ernsth Bravell M, Westerlind B, Midlöv P, Östgren CJ, Borgquist L, Lannering C, Mölstad S. How to assess frailty and the need for care? Report from the Study of Health and Drugs in the Elderly (SHADES) in community dwellings in Sweden. Arch Gerontol Geriatr. 2011 Jul-Aug;53(1):40-5. PubMed PMID: 20678818.
Hoogerduijn JG, Schuurmans MJ, Duijnstee MS, de Rooij SE, Grypdonck MF. A systematic review of predictors and screening instruments to identify older hospitalized patients at risk for functional decline. J Clin Nurs. 2007;16( 1):46-57.
Killewich LA. Strategies to minimize postoperative deconditioning in elderly surgical patients. J Am Coll Surg. 2006;203( 5):735-745
Ko FC. The clinical care of frail, older adults. Clin Geriatr Med. 2011 Feb;27(1):89-100.. PubMed PMID: 21093725.
Liu CK, Fielding RA. Exercise as an intervention for frailty. Clin Geriatr Med. 2011 Feb;27(1):101-10.. PubMed PMID: 21093726.
Luciani A, Ascione G, Bertuzzi C, Marussi D, Codecà C, Di Maria G, Caldiera SE, Floriani I, Zonato S, Ferrari D, Foa P. Detecting disabilities in older patients with cancer: comparison between comprehensive geriatric assessment and vulnerable elders survey-13. J Clin Oncol. 2010 Apr 20;28(12):2046-50. PubMed PMID: 20308657.
Mehta KM, Pierluissi E, Boscardin WJ, et al. A clinical index to stratify hospitalized older adults according to risk for new-onset disability. J Am Geriatr Soc. 2011 Jul;59(7):1206-16. doi: 10.1111/j.1532-415.2011.03409.x. Epub 2011 Jun 7. PubMed PMID: 21649616
Montero-Odasso M, Muir SW, Hall M, Doherty TJ, Kloseck M, Beauchet O, Speechley M. Gait variability is associated with frailty in community-dwelling older adults. J Gerontol A Biol Sci Med Sci. 2011 May;66(5):568-76. PubMed PMID: 21357190.
Pal SK, Katheria V, Hurria A. Evaluating the older patient with cancer: understanding frailty and the geriatric assessment. CA Cancer J Clin. 2010 Mar-Apr;60(2):120-32. PubMed PMID: 20173172.
Polidoro A, Dornbusch T, Vestri A, Di Bona S, Alessandri C. Frailty and disability in the elderly: a diagnostic dilemma. Arch Gerontol Geriatr. 2011 Mar-Apr;52(2):e75-8. PubMed PMID: 20615558
Rolland Y, Dupuy C, Abellan van Kan G, Gillette S, Vellas B. Treatment strategies for sarcopenia and frailty. Med Clin North Am. 2011 May;95(3):427-38, ix. PubMed PMID: 21549870.
Rolland Y, Onder G, Morley JE, Gillette-Guyonet S, Abellan van Kan G, Vellas B. Current and future pharmacologic treatment of sarcopenia. Clin Geriatr Med. 2011 Aug;27(3):423-47. doi: 10.1016/j.cger.2011.03.008.. PubMed PMID: 21824556
Weening-Dijksterhuis E, de Greef MH, Scherder EJ, Slaets JP, van der Schans CP. Frail institutionalized older persons: A comprehensive review on physical exercise, physical fitness, activities of daily living, and quality-of-life. Am J Phys Med Rehabil. 2011 Feb;90(2):156-68.. PubMed PMID: 20881587.
Health Services and Models of Care
Counsell SR, Holder CM, Liebenauer LL, et al. Effects of a multicomponent intervention on functional outcomes and process of care in hospitalized older patients: A randomized controlled trial of acute care for elders (ACE) in a community hospital. J Am Geriatr Soc. 2000;48( 12):1572-1581.Marengoni A, Angleman S, Melis R, Mangialasche F, Karp A, Garmen A, Meinow B, Fratiglioni L. Aging with multimorbidity: a systematic review of the literature. Ageing Res Rev. 2011 Sep;10(4):430-9. PubMed PMID: 21402176.
Rochat S, Cumming RG, Blyth F, Creasey H, Handelsman D, Le Couteur DG, Naganathan V, Sambrook PN, Seibel MJ, Waite L. Frailty and use of health and community services by community-dwelling older men: the Concord Health and Ageing in Men Project. Age Ageing. 2010 Mar;39(2):228-33. PubMed PMID: 20075036.
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