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Core Concepts

Feil DG, MacLean C, Sultzer D.Quality indicators for the care of dementia in vulnerable elders. J Am Geriatr Soc. 2007;55 Suppl 2:S293-301.

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Key Review Articles

Boeve BF. A review of the non-Alzheimer dementias. J Clin Psychiatry. 2006;67(12):1985-2001; discussion 1983-4.

Brodaty H, Breteler MM, Dekosky ST, et al. The world of dementia beyond 2020. J Am Geriatr Soc. 2011 May;59(5):923-7. doi: 10.1111/j.1532-5415.2011.03365.x. PubMed PMID: 21488846. 

Gorelick PB, Scuteri A, Black SE, et al. Vascular contributions to cognitive impairment and dementia: a statement for healthcare professionals from the American Heart Association/American Stroke Association. Stroke. 2011 Sep;42(9):2672-713.. PubMed PMID: 21778438. 

Joshi S, Morley JE. Cognitive impairment. Med Clin North Am. 2006;90( 5):769-787.

Mayeux R. Clinical practice. Early Alzheimer's disease. N Engl J Med. 2010 Jun 10;362(23):2194-201. PubMed PMID: 20558370

Querfurth HW, LaFerla FM. Alzheimer's disease. N Engl J Med. 2010;362(4):329-44. PubMed PMID: 20107219.

Petersen RC. Clinical practice. Mild cognitive impairment. N Engl J Med. 2011 Jun 9;364(23):2227-34. Review. PubMed PMID: 21651394.

Robins Wahlin TB, Byrne GJ. Personality changes in Alzheimer's disease: a systematic review. Int J Geriatr Psychiatry. 2011 Oct;26(10):1019-29. doi: 10.1002/gps.2655. PubMed PMID: 21905097.   

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Epidemiology

Barnes DE, Yaffe K. The projected effect of risk factor reduction on Alzheimer's disease prevalence. Lancet Neurol. 2011 Sep;10(9):819-28. PubMed PMID: 21775213. 

Berr C, Wancata J, Ritchie K. Prevalence of dementia in the elderly in Europe. Eur Neuropsychopharmacol. 2005;15( 4):463-471

Chapman DP, Williams SM, Strine TW, Anda RF, MooreMJ. Dementia and its implications for public health. Prev Chronic Dis. 2006;3(2):A34.

Daviglus ML, Plassman BL, Pirzada A, et al. Risk factors and preventive interventions for Alzheimer disease: state of the science. Arch Neurol. 2011 Sep;68(9):1185-90. PubMed PMID: 21555601.   

Kalaria RN, Maestre GE, Arizaga R, et al. Alzheimer's disease and vascular dementia in developing countries: prevalence, management, and risk factors. Lancet Neurol. 2008 Sep;7(9):812-26. PubMed PMID: 18667359.

Plassman BL, Langa KM, Fisher GG, et al. Prevalence of cognitive impairment without dementia in the United States. Ann Intern Med. 2008;148( 6):427-W90.

Phelan EA, Borson S, Grothaus L, Balch S, Larson EB. Association of incident dementia with hospitalizations. JAMA. 2012 Jan 1;307(2):165-72. PubMed PMID:
22235087.

Qiu C, De Ronchi D, Fratiglioni L. The epidemiology of the dementias: An update. Curr Opin Psychiatry.2007;20( 4):380-385.

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Pathophysiology

Drachman DA. Aging of the brain, entropy, and Alzheimer disease. Neurology. 2006;67( 8):1340-1352.

Jellinger KA, Attems J. Neuropathological evaluation of mixed dementia. J Neurol Sci. 2007;257( 1-2):80-87.

Jicha GA, Abner EL, Schmitt FA, et al. Preclinical AD Workgroup staging: pathological correlates and potential challenges. Neurobiol Aging. 2011  Apr 18. PubMed PMID: 21507528. 

Kelley BJ, Petersen RC. Alzheimer's disease and mild cognitive impairment. Neurol Clin. 2007;25( 3):577-609, v.

Korczyn AD, Vakhapova V. The prevention of the dementia epidemic. J Neurol Sci. 2007;257( 1-2):2-4.

Liu L , Drouet V , Wu JW , Witter MP , Small SA , et al. 2012 Trans-Synaptic Spread of Tau Pathology In Vivo. PLoS ONE 7(2): e31302. doi:10.1371/journal.pone.003130

Savva GM, Wharton SB, Ince PG, Forster G, Matthews FE, Brayne C; Medical Research Council Cognitive Function and Ageing Study. Age, neuropathology, and dementia. N Engl J Med. 2009;360(22):2302-9. PubMed PMID: 19474427.

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Assessment and Mangement

Alzheimer's Disease International. World Alzheimer Report 2011-The benefits of early diagnosis and intervention.Executive Summary. 2011

Bain LJ, Barker W, Loewenstein DA, Duara R. Towards an earlier diagnosis of alzheimer disease (proceedings of the 5th MCI symposium, 2007). Alzheimer Dis Assoc Disord. 2008;22(2):99-110.

Bouchard RW. Diagnostic criteria of dementia. Can J Neurol Sci. 2007;34 Suppl 1:S11-8

Christensen MD, White HK. Dementia assessment and management. J Am Med Dir Assoc. 2006;7( 2):109-118.

Herrmann N, Lanctot KL. Pharmacologic management of neuropsychiatric symptoms of alzheimer disease. Can J Psychiatry. 2007;52(10):630-646.

Howard R, McShane R, Lindesay J, et al. Donepezil and memantine for moderate-to-severe Alzheimer's disease. N Engl J Med. 2012 Mar 8;366(10):893-903. PubMed PMID: 22397651.

Holsinger T, Deveau J, Boustani M, Williams JW,Jr. Does this patient have dementia? JAMA. 2007;297( 21):2391-2404.

Hort J, O'Brien JT, Gainotti G, et al. EFNS guidelines for the diagnosis  and management of Alzheimer's disease.  i. 2010 Oct;17(10):1236-48. doi: 10.1111/j.1468-1331.2010.03040.x. PubMed PMID: 20831773.

Jaturapatporn D, Isaac MG, McCleery J, Tabet N. Aspirin, steroidal and non-steroidal anti-inflammatory drugs for the treatment of Alzheimer's disease. Cochrane Database Syst Rev. 2012 Feb 15;2:CD006378. PubMed PMID: 22336816.

Law LL, Barnett F, Yau MK, Gray MA. Measures of everyday competence in older adults with cognitive impairment: a systematic review. Age Ageing. 2011 Sep 4. PubMed PMID: 21893502.

McCarten JR, Anderson P, Kuskowski MA, McPherson SE, Borson S. Screening for cognitive impairment in an elderly veteran population: Acceptability and results using different versions of the mini-cog. J Am Geriatr Soc. 2011;59(2):309-313.

McKhann GM, Knopman DS, Chertkow H, et al. The diagnosis of dementia due to Alzheimer's disease: recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease. Alzheimers Dement. 2011 May;7(3):263-9.. PubMed PMID: 21514250

Manly JJ, Espino DV. Cultural influences on dementia recognition and management. Clin Geriatr Med. 2004;20(1):93-119.

McGuinness B, O'Hare J, Craig D, Bullock R, Malouf R, Passmore P. Statins for the treatment of dementia.Cochrane Database Syst Rev. 2010 Aug 4;8:CD007514. Review. PubMed PMID: 20687089.  

Rolinski M, Fox C, Maidment I, McShane R. Cholinesterase inhibitors for dementia with Lewy bodies, Parkinson's disease dementia and cognitive impairment in Parkinson's disease. Cochrane Database Syst Rev. 2012 Mar 14;3:CD006504. PubMed PMID: 22419314.

Schneider LS, Insel PS, Weiner MW; Alzheimer's Disease Neuroimaging Initiative. Treatment with cholinesterase inhibitors and memantine of patients in the Alzheimer's Disease Neuroimaging Initiative. Arch Neurol. 2011 Jan;68(1):58-66. PubMed PMID: 21220675.

Woods B, Aguirre E, Spector AE, Orrell M. Cognitive stimulation to improve cognitive functioning in people with dementia. Cochrane Database Syst Rev. 2012 Feb 15;2:CD005562. PubMed PMID: 22336813.

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Practice Guidelines

AGS Clinical Practice Committee. Guidelines abstracted from the American Academy of Neurology's dementia guidelines for early detection, diagnosis, and management of dementia. J Am Geriatr Soc. 2003;51( 6):869-873.

Daviglus ML, Bell CC, Berrettini W,et al. National Institutes of Health State-of-the-Science Conference statement: preventing alzheimer disease and cognitive decline. Ann Intern Med. 2010 Aug 3;153(3):176-81. PubMed PMID: 20547888.   

Fillit HM, Doody RS, Binaso K, et al. Recommendations for best practices in the treatment of Alzheimer's disease in managed care. Am J Geriatr Pharmacother. 2006;4 Suppl A:S9-S24; quiz S25-S28.

Goldman JS, Hahn SE, Catania JW, et al. Genetic counseling and testing for Alzheimer disease: joint practice guidelines of the American College  of Medical Genetics and the National Society of Genetic Counselors. Genet Med. 2011 Jun;13(6):597-605. PubMed PMID: 21577118.   

Lyketsos CG, Colenda CC, Beck C, et al. Position statement of the American Association for Geriatric Psychiatry regarding principles of care for patients with dementia resulting from Alzheimer disease. Am J Geriatr Psychiatry. 2006;14( 7):561-572.

Qaseem A, Snow V, Cross JT,Jr, et al. Current pharmacologic treatment of dementia: A clinical practice guideline from the American College of Physicians and the American Academy of Family Physicians. Ann Intern Med. 2008;148( 5):370-378.

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Health Services/ Models of Care

Boustani MA, Campbell NL, Khan BA,  Enhancing Care for Hospitalized Older Adults with Cognitive Impairment: A Randomized Controlled
Trial. J Gen Intern Med. 2012 Feb 3. [Epub ahead of print] PubMed PMID: 22302355.

Elliot R, Adams J. The creation of a Dementia Nurse Specialist role in an acute general hospital. J Psychiatr Ment Health Nurs. 2011 Sep;18(7):648-52. doi: 10.1111/j.1365-2850.2011.01771.x. PubMed PMID: 21848600.

Frisardi V, Imbimbo BP. Gerontechnology for demented patients: smart homes for smart aging. J Alzheimers Dis. 2011;23(1):143-6. PubMed PMID: 21157023,

Jansen AP, van Hout HP, Nijpels G, et al. Effectiveness of case management among older adults with early symptoms of dementia and their primary informal caregivers: a randomized clinical trial. Int J Nurs Stud. 2011 Aug;48(8):933-43. PubMed PMID: 21356537.

Lai CK, Yeung JH, Mok V, Chi I. Special care units for dementia individuals with behavioural problems. Cochrane Database Syst Rev. 2009 Oct 7;(4):CD006470.. PubMed PMID: 19821370. 

Williams CL, Hyer K, Kelly A, Leger-Krall S, Tappen RM. Development of nurse competencies to improve dementia care. Geriatr Nurs. 2005;26( 2):98-105.

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Social Issues

Ballard C, SorensenS, Sharp S. Pharmacological therapy for people with Alzheimer's disease: The balance of clinical effectiveness, ethical issues and social and healthcare costs. J Alzheimers Dis. 2007;12( 1):53-59.

Gallagher D, Ni Mhaolain A, Crosby L, et al. Dependence and caregiver burden in  Alzheimer's disease and mild cognitive impairment. Am J Alzheimers Dis Other Demen. 2011 Mar;26(2):110-4. PubMed PMID: 21233138. 

Iverson DJ, Gronseth GS, Reger MA, et al. Practice parameter update: evaluation and management of driving risk in dementia: report of the Quality Standards Subcommittee of the American Academy of Neurology. Neurology. 2010 Apr 20;74(16):1316-24. PubMed PMID: 20385882.

Jarrott SE. Social aspect of activity stimuli is related to positive affect in persons with Alzheimer's disease. Evid Based Nurs. 2011 Sep 25. PubMed PMID: 21949283.

Man-Son-Hing M, MarshallSC, Molnar FJ, Wilson KG. Systematic review of driving risk and the efficacy of compensatory strategies in persons with dementia. J Am Geriatr Soc.2007;55( 6):878-884

Smerglia VL, Miller NB, Sotnak DL, Geiss CA. Social support and adjustment to caring for elder family members: A multi-study analysis. Aging Ment Health. 2007;11(2):205-217.

Thompson CA, Spilsbury K, Hall J, Birks Y,Barnes C, Adamson J. Systematic review of information and support interventions for caregivers of people with dementia. BMC Geriatr. 2007;7:18.

Werner P, Goldstein D, Heinik J. Development and validity of the Family Stigma in Alzheimer's disease Scale (FS-ADS). Alzheimer Dis Assoc Disord. 2011 Jan-Mar;25(1):42-8. PubMed PMID: 20921880

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PubMed Alerts

Continuously updated PubMed searches on the following Dementia subtopics:

Classification Complications/Mortality Diagnosis Drug Therapy Economics Epidemiology Ethnology

Etiology Genetics Nursing Pathology/Physiopathology Prevention & Control Psychology Rehabilitation/Therapy

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Interdisciplinary Issues and Resources

Anderson-Hanley C, Arciero PJ, Brickman AM, Nimon JP, Okuma N, Westen SC.  Exergaming and older adult cognition: a cluster randomized clinical trial. Am J Prev Med. 2012;42(2):109-19. PubMed PMID: 22261206.

Callahan CM, Boustani MA, Unverzagt FW, et al. Effectiveness of collaborative care for older adults with Alzheimer disease in primary care: A randomized controlled trial. JAMA. 2006;295( 18):2148-2157.

Carter MD, Simms GA, Weaver DF. The development of new therapeutics for Alzheimer's disease. Clin Pharmacol Ther. 2010 Oct;88(4):475-86. PubMed PMID: 20811351.

Hindin SB, Zelinski EM. Extended practice and aerobic exercise interventions benefit untrained cognitive outcomes in older adults: a meta-analysis. J Am Geriatr Soc. 2012;60(1):136-41. doi: 10.1111/j.1532-5415.2011.03761.x.  PubMed PMID: 22150209.

Kim DH, Brown RT, Ding EL, Kiel DP, Berry SD. Dementia medications and risk of falls, syncope, and related adverse events: meta-analysis of randomized controlled trials. J Am Geriatr Soc. 2011 Jun;59(6):1019-31. doi: 10.1111/j.1532-5415.2011.03450.x. PubMed PMID: 21649634.

Moniz Cook ED, Swift K, James I, Malouf R, De Vugt M, Verhey F. Functional analysis-based interventions for challenging behaviour in dementia. Cochrane Database Syst Rev. 2012 Feb 15;2:CD006929. PubMed PMID: 22336826.

Slaughter S, Cole D, Jennings E, Reimer MA. Consent and assent to participate in research from people with dementia. Nurs Ethics. 2007;14(1):27-40.

Vernooij-Dassen M, Draskovic I, McCleery J, Downs M. Cognitive reframing for carers of people with dementia. Cochrane Database Syst Rev. 2011;11:CD005318. PubMed PMID: 22071821.

Weiss BD. Don't Forget Dementia Elder Care: A Resource for Interprofessional Providers. May 2009 (updated June 2010).

Weiss BD. Frontotemporal Dementia Elder Care: A Resource for Interprofessional Providers.June 2009 (updated June 2010).

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